Designing the Future of Medicine: an Artificial Red Blood Cell

Built to Optimize Traditional Functions and Enable Proactive Diagnosis and Treatment of Infections

My Proposal: Artificial Red Blood Cell

More specifically, polyethylene glycol-polylactic acid copolymer nanocapsule encapsulating polyhemoglobin-superoxide dismutase-catalase-carbonic anhydrase, Apabetalone, the chemical inhibitor of CD47-SIRPα, Cyclodextrin-statin, Aliskiren and Midodrine. The nanocapsule’s surface is configured with polyethylene glycol, oxLDL, tissue plasminogen activator, various antibodies, bradykinin receptors and renin receptors.



Quick Information

PolyHb-SOD-CAT-CA — Oxygen and Carbon Dioxide Transport + Antioxidant Mechanism

Visualization of the interactions of O₂ and CO₂ with a traditional tissue cell. Source

Polyethylene Glycol — Evading the RES

Process of Opsonization. Opsonin (blue), Nanoparticle (Red) and Phagocyte (Yellow). Source
Example of a PEG-coated gold nanoparticle. Source

Polyethylene Glycol — Polylactic Acid Copolymer Membrane

Proactive Diagnosis and Treatment of Atherosclerosis

Oversimplified diagram of reverse cholesterol transport. Cholesterol (blue), HDL (green). Source

Regulating Blood Pressure

Diagnosis to Treatment of Infections


Solving Blood Incompatibility

Nanocapsule Production

Diagram of each step of emulsion. Source
Another representation of the process of emulsion solvent evaporation. Source

Final Thoughts

Thanks for Reading!

15-year-old Nanotechnology enthusiast whose mission is to use technology to solve real-world problems.